Welcome from
Helen Matthews, CEO
As the year gathers momentum, it’s a pleasure to pause and welcome you to this edition of our newsletter. It’s been a busy and energising few months. Not only have we seen some exciting and tangible progress in Parkinson’s research, but you, our supporters, have been keeping us on our toes with your incredible efforts to raise funds and awareness to support our work to find a cure.
We have seen positive progress with the phase 3 trials of Ambroxol for Parkinson’s (ASPro-PD) and The Edmond J Safra Accelerating Clinical Trials in Parkinson’s Disease (EJS ACT-PD), which are both advancing with recruitment.
Our recent initiative to support clinical investigations of combination therapies is making headway. A panel of Parkinson’s experts are in the process of reviewing grant applications for up to £2 million of support from Cure Parkinson’s for projects that use two or more drugs in combination with the aim of developing a disease-modifying treatment for Parkinson’s.
I am delighted that nominations are now open for the Tom Isaacs Award. This hugely important award is jointly presented each year by Cure Parkinson’s and Van Andel Institute to honour a researcher who has made an impact on and involved people with Parkinson’s in their work. Involving people with lived experience of the condition is critical if we are to improve our understanding of Parkinson’s and advance research towards a cure.
We marked Parkinson’s Awareness Month in April with My Story: Our Cure, which featured some very special contributions from a group of inspiring supporters who shared a glimpse of their lives with Parkinson’s to help raise awareness of the condition.
Thank you to everyone who voted for our film A Question of Time in the Smiley Charity Film Awards, which features the stories of four extraordinary supporters who live with Parkinson’s. The film has been making an impact over the last year, helping us raise funds and awareness of Parkinson’s, so to see it win the Bronze People's Choice Award was a wonderful moment and a tribute to everyone who took part.
Our work is only possible with your support so it is really important to us that we are directing our energy and resource into the things that matter to you. So please do take a few minutes to complete our supporter survey.
Your opinion is important to us. Thank you for your continued support - we are so grateful to have you with us as we work tirelessly towards a cure for Parkinson’s.
Helen Matthews, CEO, Cure Parkinson’s
Our research
Read about our research progress, the latest projects we are funding and how you can get involved.
An update on our funded projects
Last year, we celebrated the launch of two late-stage clinical trials in the UK – EJS ACT-PD and ASPro-PD. With both trials well into their recruitment phases, we are pleased to give an update on their progress.
Inflammation and Parkinson's in focus
Our recent Spring Research Update Meeting was centred around inflammation and Parkinson’s, featuring two of our funded researchers who are currently studying treatments targeting neuroinflammation.
An update on our combination therapies funding call
Last October, Cure Parkinson’s announced the launch of a new funding call which asked researchers to propose studies involving rationally designed combination therapies.
Our grant funding programmes
In addition to the combination therapies funding call, Cure Parkinson’s has two regular funding programmes - our quarterly research grant funding programme and our iLCT pipeline research acceleration programme. Learn more about the process for each of these grant calls.
Tom Isaacs Awards: nominations now open
Each year, together with Van Andel Institute (VAI), Cure Parkinson’s recognises a researcher whose work demonstrates scientific excellence, partnership, compassion and a determination to make a meaningful difference to people affected by Parkinson’s.
Shake Well Before Use: From Coastin' to Cure Parkinson's
As a thank you to all of our incredible supporters at the end of our 20th anniversary year, we shared an audiobook journey like no other. Listen to Shake Well Before Use, written and narrated by our late Co-founder and President Tom Isaacs, one chapter at a time.
Stay involved with our research
Catch up with and look ahead to some of our key research events for the year, which give attendees the opportunity to hear the latest developments in Parkinson’s research and updates on our research funding. Additionally, find out how you can join our advocacy community helping to support our mission.
Our fundraising
Learn about our latest fundraising successes and how you can help support our work to find a cure.
My Story: Our Cure
Everyone’s experience with Parkinson’s is different. Every person has a different story to tell. But in the end, we are all connected by one simple goal - a cure. Find out more about seven of our most passionate supporters.
Something to smile about
We were delighted to have been shortlisted in the 2026 Smiley Charity Film Awards for our film A Question of Time, and are thrilled to announce we won Bronze in their People’s Choice award thanks to you, our incredible supporters!
Inform our work by taking part in our supporter survey
Cure Parkinson’s wants to hear from you! We’re inviting you to take part in a new survey so we can hear your thoughts about our organisation and our work, and learn how we can better meet your needs.
Our fundraising heroes
Each year Cure Parkinson’s celebrates a fundraiser who has gone above and beyond to support our vital Parkinson’s research. To keep up with the charity’s growing size and give us the chance to celebrate more of the challenges you – our incredible supporters – haven taken on, we’ve decided to award three winners for 2025!
Running for a cure
This April, our dedicated supporters once again took on the iconic TCS London Marathon for Cure Parkinson’s. 54 incredible runners completed the 26.2-mile race as Team Cure, including Lottie Coulson, who shares why she used her ballot place to fundraise for Cure Parkinson’s.
Fundraising in your community: footstepping for a cure
There are many ways to get involved with your community whilst fundraising for Cure Parkinson’s. This year, we would like to highlight the incredible efforts of Footsteps Nursery for spending four months fundraising in aid of our Parkinson’s research.
Team Cure needs your support
Our research is not only powered by our incredible fundraisers, but also by those who kindly donate their time to help push us forward to a cure.
Walk to Cure Parkinson's returns for 2026
Whether you take part with family, friends or colleagues, walk for yourself or in memory of a loved one – join us, and together we will find a cure.
Cure Parkinson's Gala Evening
Join us for an extraordinary gala evening at the Natural History Museum in support of Cure Parkinson’s.
Cure InSight Digital Survey
We created a digital version of Cure InSight thanks to feedback from our supporters. Your thoughts on this edition would be greatly appreciated and will help inform how we create future editions.
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